Where each model wins for clinic workflows
Post-order pricing works well when a clinic already has cost data from prior order history, when it does not quote cash-pay patients on a per-vial basis before the consult, or when the relationship with Wells is long-standing enough that per-Rx cost is predictable without checking before every order. The upside of the Wells model is simplicity and a free portal: WellsPx3 is free to registered customers, per Wells' public documentation, and the platform handles DEA 1311-certified electronic ordering, WPNScripts e-prescribing, and order management in one place. If the practice only orders from Wells and the workflow is prescription-by-prescription, the post-placement pricing record may be all that is needed.
Pre-checkout pricing wins when a clinic needs to quote cash-pay patients on per-vial cost before the consult, wants to batch the entire refill day in one cart and see total COGS before a single payment, or is evaluating multiple 503A partners and needs cost on every SKU before deciding which to use for which patient. Most cash-pay GLP-1 and hormone clinics fall into this category because setting patient program pricing requires knowing per-vial cost in advance, not confirming it after the prescription has been placed.