What a clinic owner can and cannot plan up front
You can plan patient price points, refill cadence, and which SKUs drive volume. What you cannot plan up front with VSDH is the COGS number itself, because wholesale per-vial rates are partner-gated. You also cannot fully model platform overhead until you know the annual license, revenue-share percentage, and whether VSDHOne state licenses apply. That gap matters most for high-volume GLP-1 programs, where a small per-vial difference plus a revenue-share layer multiplied across hundreds of monthly refills swings the bottom line.
Before margin depends on it, ask for written per-vial wholesale on your top three SKUs, the revenue-share basis and percentage on pharmacy orders, and whether shipping and cold-chain handling are included in wholesale or billed separately. Build your margin model on the all-in delivered cost per vial plus platform economics amortized across expected order volume — not a headline wholesale rate from a sales deck.