Fizy health
Refill software fees vs drug fees

Does Refill charge a software fee on top of drug cost?

Yes. Refill publicly separates aggregate pre-negotiated 503A medication pricing from tiered software fees on transactions, published at roughly 1.5–5% depending on platform plan, plus monthly platform subscriptions from free to about $299 on published tiers. Medication cost reflects network leverage; software fees scale with order spend. Knowing both layers matters because a competitive aggregate drug rate paired with a higher software fee tier can cost more than pass-through pricing with a single disclosed facilitation fee at your actual volume.

This page separates Refill's medication and software fee layers and shows how to compute total cost of ownership against pass-through pricing.

Compare Fizy Health vs Refill
Software fees 1.5–5% Aggregate drug rates Platform tiers to $299/mo Total cost of ownership Disclosed facilitation fee GLP-1 volume math

The two published layers in Refill pricing

Refill's public pricing structure names both layers. Aggregate pre-negotiated 503A medication rates are the drug layer, negotiated across network volume and confirmed per SKU at demo. Software fees on transactions are the platform layer, published at roughly 1.5–5% depending on tier, plus optional monthly platform subscription and Refill Connect charges. Unlike platforms that fold economics into one opaque rate, Refill publishes the software fee range, but medication rates are still aggregate rather than per-line pass-through, so total cost of ownership requires adding both layers plus shipping and any provider encounter fees.

Why the split changes total cost of ownership

Two clinics on different Refill tiers can pay the same aggregate semaglutide rate but different software fee percentages. A fixed monthly platform fee is cheap per vial at high volume and expensive at low volume. A percentage software fee scales with every GLP-1 refill. Compute total cost of ownership over a representative month: sum of per-vial medication cost times line count, plus software fee percentage on transaction totals, plus monthly platform and Connect charges prorated per vial, plus shipping.

This is where a competitive aggregate drug rate can mislead. High GLP-1 transaction counts multiply software fee dollars. The honest comparison adds the software layer back in before you judge whether Refill beats alternatives on your highest-volume SKUs.

How a single disclosed facilitation fee compares

Fizy Health structures economics for margin transparency: resolved per-vial 503A drug cost on each catalog and cart line before checkout, and a single facilitation fee disclosed at payment. No percentage software fee on transactions and no monthly platform fee on the free plan. Total cost of ownership is visible drug cost plus named fee, computable before you order.

When you evaluate Refill, confirm your tier's exact software fee percentage at demo, add it to aggregate medication rates across your actual monthly order count, and compare that total against visible pass-through cost plus facilitation fee on the same SKUs. Total-to-total comparison wins, not drug-rate-to-drug-rate.

Model two Refill layers — or read drug cost and one fee?

Refill fits if

Refill

Aggregate drug rates plus published software fees work at your tier and volume.

  • Pre-negotiated medication rates plus your tier's software fee beat pass-through on top SKUs at your order count.
  • You need Refill Connect or outsourced prescribing and accept percentage fees on transactions.
  • You will compute total cost of ownership from demo-confirmed rates and published tier fees.
Consider Fizy Health if

Fizy Health

You prescribe in-house and want drug cost and one fee visible.

  • You want resolved 503A drug cost per line with a single facilitation fee, no percentage transaction fee.
  • You want total cost of ownership computable before demo and onboarding.
  • You want to avoid software fees compounding on every GLP-1 refill in a high-volume week.
If you choose Fizy Health

What you get when fee layers are legible.

Refill splits aggregate drug cost and percentage software fees. These outcomes use one disclosed facilitation fee.

See all features
Keep evaluating Refill pricing

More on Refill cost components.

See the full Refill pricing guide
FAQ

What clinics ask about Refill software vs drug fees.

  • Software fee

    What software fees does Refill charge?

    Published Refill tiers show transaction software fees roughly between 1.5% and 5% depending on platform plan, plus monthly subscriptions from free to about $299. Refill Connect adds separate monthly, setup, and transaction fees.

  • Separation

    Are Refill drug and software fees separate?

    Yes in structure. Aggregate pre-negotiated medication rates are the drug layer; software fees on transactions are the platform layer. Both must be included in total cost of ownership.

  • Total cost

    Why does the fee split matter?

    Percentage software fees scale with order spend. High GLP-1 volume multiplies software fee dollars even when aggregate medication rates look competitive. Total cost beats headline drug rate.

  • Tiers

    How does platform tier affect software fees?

    Higher Refill tiers may change the software fee percentage within the published roughly 1.5–5% range and add monthly platform cost. Confirm your exact percentage at demo.

  • Comparison

    How does Fizy Health structure software vs drug cost?

    Fizy Health passes through per-vial 503A drug cost shown on each line and discloses a single facilitation fee at payment, with no percentage software fee on transactions.

  • Method

    How do I compare total cost between platforms?

    Add Refill aggregate medication cost plus software fee percentage plus platform subscription across a representative month, then compare to visible pass-through cost plus facilitation fee on the same SKUs and volume.

Sources reviewed June 2026

  • Refill public website and published pricing tiers in Refill web app (refill.co), reviewed June 2026.
  • Fizy Health platform capabilities reflect the live product.
Evaluate with real numbers

Compare total cost, not just the drug rate.

See per-vial drug cost and one disclosed fee, compute total cost of ownership, and compare against Refill's two-layer model. Free to start.

Start Ordering Free Fizy Health vs Refill