Standalone is fine until you need data to move
Many clinics run an clinic ordering portal as a standalone tool and accept manual re-entry between it and their EMR. That works at small scale. As volume grows, the absence of integration becomes a tax: patient details retyped, orders reconciled by hand, reporting stitched together across systems. Whether that matters depends on your operation.
Because Refill does not document a public API or named integrations, ask concretely: is there an API, what EMRs are supported, can ordering data be exported, and in what format? Do not assume connectivity from the consolidated-dashboard pitch — dashboard consolidation across pharmacies is different from integration with your other systems.